Brazilian spotted fever prevention through a nonlethal capybara population control strategy

Derek Andrew Rosenfield; Gina Polo; Cristiane Schilbach Pizzutto

doi:10.1590/0037-8682-0156-2019

Brazilian spotted fever prevention through a nonlethal capybara population control strategy

Derek Andrew Rosenfield, Gina Polo, Cristiane Schilbach Pizzutto

Universidade de São Paulo

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Introduction: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000-2018 >600 human deaths) involving synanthropic capybara as host. Methods: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. Results: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas. Conclusions: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.

Original language	English
Article number	e20190156
Journal	Revista da Sociedade Brasileira de Medicina Tropical
Volume	52
DOIs	https://doi.org/10.1590/0037-8682-0156-2019
State	Published - 2019
Externally published	Yes

Keywords

Amblyomma sculptum
Anti-GnRH
GonaCon
Hydrochoerus hydrochaeris
Immunocontraception
Rickettsia

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1590/0037-8682-0156-2019

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title = "Brazilian spotted fever prevention through a nonlethal capybara population control strategy",

abstract = "Introduction: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000-2018 >600 human deaths) involving synanthropic capybara as host. Methods: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. Results: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas. Conclusions: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.",

keywords = "Amblyomma sculptum, Anti-GnRH, GonaCon, Hydrochoerus hydrochaeris, Immunocontraception, Rickettsia",

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year = "2019",

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volume = "52",

journal = "Revista da Sociedade Brasileira de Medicina Tropical",

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T1 - Brazilian spotted fever prevention through a nonlethal capybara population control strategy

AU - Rosenfield, Derek Andrew

AU - Polo, Gina

AU - Pizzutto, Cristiane Schilbach

PY - 2019

Y1 - 2019

N2 - Introduction: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000-2018 >600 human deaths) involving synanthropic capybara as host. Methods: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. Results: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas. Conclusions: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.

AB - Introduction: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000-2018 >600 human deaths) involving synanthropic capybara as host. Methods: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. Results: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas. Conclusions: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.

KW - Amblyomma sculptum

KW - Anti-GnRH

KW - GonaCon

KW - Hydrochoerus hydrochaeris

KW - Immunocontraception

KW - Rickettsia

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DO - 10.1590/0037-8682-0156-2019

M3 - Article

C2 - 31596349

AN - SCOPUS:85073068297

SN - 0037-8682

VL - 52

JO - Revista da Sociedade Brasileira de Medicina Tropical

JF - Revista da Sociedade Brasileira de Medicina Tropical

M1 - e20190156

ER -

Brazilian spotted fever prevention through a nonlethal capybara population control strategy

Abstract

Keywords

UN SDGs

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