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Andamios de magnesio: avances enreparación ósea

Translated title of the contribution: Magnesium scaffolds: advances in bone healing
  • Pennsylvania State University
  • Universidad Pontificia Bolivariana
  • Universidad Nacional de Colombia

Research output: Contribution to conferenceAbstractpeer-review

Abstract

This research is about designing a special environment that helps bones grow and repair themselves, particularly when dealing with large bone injuries. We are exploring the use of metals that can dissolve in the body over time and have a porous, sponge-like structure. These metals, specifically Magnesium or Mg, can help to bridge the gap between the healthy parts of the bone tissue when the bone’s natural healing ability is not enough. One of the unique qualities of these Mg structures is that they are strong yet flexible, adjusting to the bone’s changing needs during the healing process. They can also guide the growth of new tissue and blood vessels. Another neat feature is that as the Mg dissolves, it releases particles (Mg2+ions) that can speed up the healing process.
However, there are some challenges. First, Mg dissolves too quickly, which can make it difficult to properly merge with the tissue. Also, the sponge-like structure of Mg accelerates its breakdown, and the complex shapes we are designing can make it hard to apply existing methods to protect the metal from fast dissolving. Hence, in this research, our goal is to create a new type of Mg scaffold for bone replacement. This scaffold will have a porous structure and will be designed to be more resistant to breakdown and more compatible with the body. We have experimented with different architectures and found some promising results with random pores, cut-off octahedron shapes, and diamond-like structures.
Translated title of the contributionMagnesium scaffolds: advances in bone healing
Original languageSpanish
Pages389-392
DOIs
StatePublished - Oct 2023
Externally publishedYes

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