Accidental oral paraphenylenediamine poisoning in a 5 year-old child

César A. Zuluaga; Pilar J. Acosta; Camilo Acevedo; Diana Bravo; Ledys M. Izquierdo; Armando León

doi:10.1016/j.acci.2018.06.009

Accidental oral paraphenylenediamine poisoning in a 5 year-old child

César A. Zuluaga, Pilar J. Acosta, Camilo Acevedo, Diana Bravo, Ledys M. Izquierdo, Armando León

Research output: Contribution to journal › Article › peer-review

Abstract

Para-phenylenediamine (PPD) is an aromatic amine used in cosmetics and industrial applications. The PPD lethal dose in adults is estimated at 7 grams or more. The toxic effects of PPD are dose-related. Despite being highly toxic, its use is not restricted, especially in underdeveloped countries. Treatment consists primarily of advanced life support. PPD poisoning has a high mortality and morbidity, with multiorgan dysfunction. The case is presented of a school child with accidental poisoning PPD, who established a rapid respiratory failure with the development of liver damage, and cardiac and renal failure. During his hospitalization in the Paediatric Intensive Care Unit he required cardiovascular support, ventilatory support, and renal replacement therapy. The patient was discharged from critical care a week after full recovery.

Translated title of the contribution	Intoxicación oral accidental por parafenilendiamina en niño de 5 años
Original language	English
Pages (from-to)	37-40
Number of pages	4
Journal	Acta Colombiana de Cuidado Intensivo
Volume	19
Issue number	1
DOIs	https://doi.org/10.1016/j.acci.2018.06.009
State	Published - 01 Jan 2019
Externally published	Yes

Keywords

Angio-neurotic oedema
Phenylenediamine
Poisoning
Rhabdomyolysis

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10.1016/j.acci.2018.06.009

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title = "Accidental oral paraphenylenediamine poisoning in a 5 year-old child",

abstract = "Para-phenylenediamine (PPD) is an aromatic amine used in cosmetics and industrial applications. The PPD lethal dose in adults is estimated at 7 grams or more. The toxic effects of PPD are dose-related. Despite being highly toxic, its use is not restricted, especially in underdeveloped countries. Treatment consists primarily of advanced life support. PPD poisoning has a high mortality and morbidity, with multiorgan dysfunction. The case is presented of a school child with accidental poisoning PPD, who established a rapid respiratory failure with the development of liver damage, and cardiac and renal failure. During his hospitalization in the Paediatric Intensive Care Unit he required cardiovascular support, ventilatory support, and renal replacement therapy. The patient was discharged from critical care a week after full recovery.",

keywords = "Angio-neurotic oedema, Phenylenediamine, Poisoning, Rhabdomyolysis",

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doi = "10.1016/j.acci.2018.06.009",

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T1 - Accidental oral paraphenylenediamine poisoning in a 5 year-old child

AU - Zuluaga, César A.

AU - Acosta, Pilar J.

AU - Acevedo, Camilo

AU - Bravo, Diana

AU - Izquierdo, Ledys M.

AU - León, Armando

PY - 2019/1/1

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N2 - Para-phenylenediamine (PPD) is an aromatic amine used in cosmetics and industrial applications. The PPD lethal dose in adults is estimated at 7 grams or more. The toxic effects of PPD are dose-related. Despite being highly toxic, its use is not restricted, especially in underdeveloped countries. Treatment consists primarily of advanced life support. PPD poisoning has a high mortality and morbidity, with multiorgan dysfunction. The case is presented of a school child with accidental poisoning PPD, who established a rapid respiratory failure with the development of liver damage, and cardiac and renal failure. During his hospitalization in the Paediatric Intensive Care Unit he required cardiovascular support, ventilatory support, and renal replacement therapy. The patient was discharged from critical care a week after full recovery.

AB - Para-phenylenediamine (PPD) is an aromatic amine used in cosmetics and industrial applications. The PPD lethal dose in adults is estimated at 7 grams or more. The toxic effects of PPD are dose-related. Despite being highly toxic, its use is not restricted, especially in underdeveloped countries. Treatment consists primarily of advanced life support. PPD poisoning has a high mortality and morbidity, with multiorgan dysfunction. The case is presented of a school child with accidental poisoning PPD, who established a rapid respiratory failure with the development of liver damage, and cardiac and renal failure. During his hospitalization in the Paediatric Intensive Care Unit he required cardiovascular support, ventilatory support, and renal replacement therapy. The patient was discharged from critical care a week after full recovery.

KW - Angio-neurotic oedema

KW - Phenylenediamine

KW - Poisoning

KW - Rhabdomyolysis

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JF - Acta Colombiana de Cuidado Intensivo

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Accidental oral paraphenylenediamine poisoning in a 5 year-old child

Abstract

Keywords

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