Latin American Aspergillus fumigatus Azole Resistance Survey in 12 countries

2 Project Objectives1. To evaluate the presence of azole-resistant A. fumigatus isolates in air samples in Latin America.2. To assess the presence of mutations in the Cyp5 IA gene of azole-resistant A. fumigatus isolates.3. To compare the genetic relationship between resistant strains found in the air of different countries ofLatin America.4. To evaluate the relationship between the use of azole agricultural fungicides and the presence of azole-resistant A. fumigatus isolates.5. Establish a Network in Latin America for resistance monitoring of Aspergillus and other studies that can be carried out afterwards.