Overview
Personal profile
Personal profile
Full Professor and researcher at the Pontifical Xavierian University, with extensive experience in immunology, molecular oncology, antitumor immunotherapy, and the development of phytomedicines. Her work focuses on translational research and the development of innovative therapeutic alternatives against cancer based on natural products, integrating basic research, preclinical development, and technology transfer.
She holds a degree in Bacteriology from the Pontifical Xavierian University, an MSc in Immunology from the University of Antioquia, an MSc in Molecular Oncology from the Centro de Estudios Biosanitarios in Madrid (Spain), and a PhD in Immunology from Université Pierre et Marie Curie (France). She completed postdoctoral training in antitumor immunotherapy and molecular immunology at Saint Louis and Necker Hospitals in Paris.
She currently serves as Scientific Director and CEO of DreemBio S.A.S., a Colombian biotechnology startup focused on the development of phytomedicines for cancer and immune modulation, and as Scientific Director of Phairilab (France). She has led major science, technology, and innovation initiatives, including the GAT ecosystem program “Generation of Therapeutic Alternatives Against Cancer from Plants” and the NIDO program “Strengthening Productive Chains: Biodiversity in Health”.
Her expertise includes tumor immunology, immunogenic cell death, immunometabolism, bioactive natural products, preclinical development of antitumor therapies, murine cancer models, technology transfer, and intellectual property management. She is co-inventor of more than 12 patents granted in the United States, Canada, Europe, Brazil, and Colombia, currently transferred to DreemBio.
She has led multiple interdisciplinary national and international collaborations focused on the use of biodiversity for applications in human health. She is a member of the Colombian Academy of Exact, Physical and Natural Sciences.
Expertise and Research Capabilities
- Tumor immunology and immunotherapy
- Development of phytomedicines and bioactive natural products
- Translational cancer research
- Immunometabolism and tumor microenvironment
- Preclinical murine models
- Development and preclinical validation of antitumor therapies
- Technology transfer and intellectual property
- Biodiversity-based innovation for human health
- Strategic leadership in R&D&I programs
- Biotechnology startup development
Education
PhD, Doctor in Immunology
Award Date: 09 Jul 2002
Master, Master in Immunology
Award Date: 01 May 1990
Bachelor, Bacteriologist
Award Date: 01 Jan 1983
Category in the National Science System 2024
- Senior
Associated academic programs - Bogotá
- Bacteriology
- Biology
- Doctorate in Biological Sciences
- Specialization in Oncological Surgery
- Specialization in Mastology
- Specialization in Clinical Oncology
- Specialization in Radiotherapy
- Master's Degree in Bioengineering
- Master's Degree in Biological Sciences
- Master's Degree in Clinical Laboratory Sciences
- Industrial Microbiology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Chemical composition and screening of the dermatological potential of chrysalis extract from Bombyx mori L. Hybrid pílamo 1
Guerrero, G. E., Mejía, M. S., Baena, L. M., Fiorentino, S. & Ballesteros-Ramírez, R., 03 Jan 2026, In: Natural Product Research.Research output: Contribution to journal › Article › peer-review
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Chemical composition and biological activity of ethanolic leaf extract from Tillandsia usneoides in a murine model of acute myeloid leukemia
Rojas, L., Lasso, P., Murillo, N., Costa, G. M. & Fiorentino, S., Sep 2025, In: Advances in Traditional Medicine. 25, 3, p. 763-776 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Modulation of Tumor Metabolism in Acute Leukemia by Plant-Derived Polymolecular Drugs and Their Effects on Mitochondrial Function
Arévalo, C., Carlosama, C., Rojas, L., Cala, M. P., Hamon, M. P., Friguet, B., Barreto, A. & Fiorentino, S., Apr 2025, In: Molecules. 30, 8, 1783.Research output: Contribution to journal › Article › peer-review
Open Access -
Petiveria alliacea and Caesalpinia spinosa extracts reduce the generation of cancer-associated fibroblasts in a 3D platform representative of the tumor microenvironment
Jimenez, M. C., Lasso, P., Fiorentino, S. & Barreto, A., 02 Jul 2025, In: Cancer Cell International. 25, 1, p. 243 243.Research output: Contribution to journal › Article › peer-review
Open Access -
The potential of phytomedicines to optimize CAR-T cell therapy in cancer
Covo-Vergara, Á., De ulzurrun-Ripa, U. D., Smerdou, C., Hernández-Rueda, M., Estrada-Palafox, D. G., Ureña, C., Hervas-Stubbs, S., Fiorentino, S. & Garcia-Garcia, M. R., 19 Sep 2025, In: Immunotherapy. 17, 13, p. 953-966 14 p.Research output: Contribution to journal › Review article › peer-review
Projects
- 75 Finished
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Plant Extracts Modulate Cellular Stress to Inhibit Replication of Mouse Coronavirus MHV-A59
Fiorentino Gomez, S. (CoI) & Barreto Prieto, A. (Other)
17/11/23 → 01/03/24
Project: Research
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Effect of Petiveria alliacea extracts on metabolism of K562 my-eloid leukemia cells.
Fiorentino Gomez, S. (Other)
16/11/23 → 16/12/23
Project: Research
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Implementación de estrategias adecuadas de monitorización inmunológica y caracterización clínica en pacientes VIH+ en diferentes fases de la enfermedad y en pacientes con linfomas asociados a SIDA.
Quijano Gomez, S. M. (PI), Fiorentino Gomez, S. (CoI), Gualtero Trujillo, S. M. (CoI) & Valderrama Beltran, S. L. (CoI)
15/02/22 → 14/02/26
Project: Research
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Evaluación de las propiedades del extracto de la microalga Galdieria sp. USBA-GBX 832 para su aplicación en salud y cosmecéutica
López Ramírez, G. P. (PI), Barreto Prieto, A. (CoI), Fiorentino Gomez, S. (CoI), Gonzalez-Barrios, A. F. (CoI), Restrepo Restrepo, S. (CoI), Vera Bravo, R. (CoI), Quevedo Hidalgo, B. E. (CoPI) & Parada-Pinilla, M. P. (Asis)
15/02/22 → 30/04/25
Project: Research
Press/Media
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Pontifical University Javeriana Researchers Have Provided New Data on Acute Lymphoblastic Leukemia (IL-8 in bone marrow and peripheral blood of patients with B-cell acute lymphoblastic leukemia is associated with high regulatory T cell counts, ...)
Fiorentino Gomez, S., Solano Vega, J. C. & Quijano Gomez, S. M.
08/10/24
1 item of Media coverage
Press/Media
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Pontifical University Javeriana Researchers Describe Recent Advances in Breast Cancer (Triple negative breast cancer migration is modified by mitochondrial metabolism alteration induced by natural extracts of C. spinosa and P. alliacea)
Fiorentino Gomez, S., Barreto Prieto, A. & Uruena Pinzon, C. P.
17/09/24
1 item of Media coverage
Press/Media
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Study Findings on Melanoma Are Outlined in Reports from Pontifical University Javeriana (Natural Products Induce Different Anti-Tumor Immune Responses in Murine Models of 4T1 Mammary Carcinoma and B16-F10 Melanoma)
Fiorentino Gomez, S. & Uruena Pinzon, C. P.
21/12/23
1 item of Media coverage
Press/Media
Prizes
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Best Research Papers - Paper-Prize: Evaluation of chemotherapy and P2Et extract combination in ex vivo derived tumor mammospheres from breast cancer patients
Fiorentino Gomez, S. (Recipient), A. SANDOVAL, T. (Recipient), Lasso Apráez, P. V. (Recipient), Tawil Moreno, M. (Recipient), Barreto Prieto, A. (Recipient), Torregrosa Almonacid, L. (Recipient) & Uruena Pinzon, C. P. (Recipient), 2021
Prize
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Best Research Works - Work Award: Bioactive Fraction of Petiveria
Fiorentino Gomez, S. (Recipient), CLAUDIA CIFUENTES, M. (Recipient), Uruena Pinzon, C. P. (Recipient), FREDY HERNÁNDEZ, J. (Recipient), Herrera Castañeda, D. P. (Recipient) & Santander Gonzalez, S. P. (Recipient), 2015
Prize
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Research Congress at the Pontifical Javeriana University - 2011
Fiorentino Gomez, S. (Recipient), 2019
Prize
Impacts
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Instituto de Biodiversidad, Bioeconomía e Innovación en Salud
Fiorentino Gomez, S. (Participant), Suarez Venegas, D. R. (Participant), Prieto Sandoval, J. V. (Participant) & Fernandez-Sanchez, M. J. (Participant)
Impact
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